私立大学戦略的研究基盤形成支援事業 機能性ナノ単一サイズ有機分子創製センター 関西学院大学 理工学部 Keansei Gakuin Univ., School of Science and Technology

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学術論文

山田英俊
(1)Total Syntheses of Laevigatins A and E. Hirokane, T.; Ikeuchi, K.; Yamada, H. Eur. J. Org. Chem. 2015, 7352–7359.
(2)Direct thiophenylation accompanying orthoester-cleavage of 1,2,4-O-orthoacetyl-3,6-O-(o-xylylene)glucopyranose. Uchino, T.; Tomabechi, Y.; Fukumoto, A.; Yamada, H. Carbohydr. Res. 2015, 402, 118–123.
(3) Electrochiroptical Response in Aqueous Media: 9,10-dihydrophenanthrene-9,10-diyl Dications with Michlar’s Hydrol Blue Chromophores Attached with Oligoethylene Glycol Units. Suzuki, T.; Hanada, K.; Katoono, R.; Ishigaki, Y.; Higasa, S.; Higuchi, H.; Kikuchi, H.; Fujiwara, K.; Yamada, H.; Fukushima, T. Chem. Lett. 2014, 43, 982–984.
(4)A Unified Strategy for the Synthesis of Highly Oxygenated Diaryl Ethers Featured in Ellagitannins. Hirokane, T.; Hirata, Y.; Ishimoto, T.; Nishii, K.; Yamada, H. Nat. Commun. 2014, 5, 3478.
(5)Total Synthesis of Cercidinin A. Yamada, H.; Ohara, K.; Ogura, T. Eur. J. Org. Chem. 2013, 7872–7875.
(6)Synthesis of Ellagitannins Containing Axial-Rich Glucose. Yamada, H.; Ikeda, Y.; Nagao, K.; Kasai, Y. Journal of Synthetic Organic Chemistry, Japan, 2013, 71, 1051–1060.
(7)Synthesis of 3,6-O-(o-xylylene)glucopyranosyl fluoride, an Axial-Rich Glycosyl Donor of β-glycosylation. Asakura, N.; Motoyama, A.; Uchino, T.; Tanigawa, K.; Yamada H. J. Org. Chem. 2013, 78, 9482–9487.
(8)Roxbin B is Cuspinin; Structural Revision and Total Synthesis. Yamaguchi, S.; Hirokane, T.; Yoshida, T.; Tanaka, T.; Hatano, T.; Ito, H.; Nonaka, G.; Yamada, H. J. Org. Chem. 2013, 78, 5410–5417.
(9)Oxidative Conversion of Tetraaryldihydrodibenzothiepins into Elemental Sulfur and Stable Cationic Dyes Accompanied by Dual UV-Vis and CD Spectral Changes. Suzuki, T.; Kuroda, T.; Tamaoki, H.; Higasa, S.; Katoono, R.; Fujiwara, K.; Fukushima, T.; Yamada, H. Chem. Lett. 2013, 42, 706–708.
(10)High Yield Total Synthesis of (–)-Strictinin through Intramolecular Coupling of Gallates. Michihata, N.; Kaneko, Y.; Kasai, Y.; Tanigawa, K.; Hirokane, T.; Higasa, S.; Yamada, H. J. Org. Chem. 2013, 78, 4319–4328.

羽村季之
(11)Selective Halogen–Lithium Exchange of 1,2-dihaloarenes for Successive [2+4] Cycloadditions of Arynes and Isobenzofurans. Eda, S.; Hamura, T. Molecules. 2015, 19449–19462. (Special Issue in Development and Application of Aryne Chemistry).
(12)Ring Selective Generation of Isobenzofuran for Divergent Access to Polycyclic Aromatic Compounds. Akita, R.; Kawanishi, K.; Hamura, T. Org. Lett. 2015, 17, 3094–3097.
(13)New Synthetic Route to Substituted Tetracenes and Pentacenes via Stereoselective [4+2] Cycloadditions of 1,4-dihydro-1,4-epoxynaphthalene and Isobenzofuran. Eda, S.; Eguchi, F.; Haneda, H.; Hamura, T. Chem. Commun. 2015, 51, 5963.
(14)An Efficient Synthetic Route to 1,3-bis(arylethynyl)isobenzofuran by Using Alkoxybenzocyclobutenone as a Reactive Platform. Asahina, K.; Matsuoka, S.; Nakayana, R.; Hamura T. Org. Biomol. Chem. 2014, 12, 9773–9776.
(15)Dibromoisobenzofuran as a Formal Equivalent of Didehydroisobenzofuran: Reactive Platform for Expeditious Assembly of Polycycles. Haneda, H.; Eda, S.; Aratani, M.; Hamura, T. Org. Lett. 2014, 16, 286–289.
(16)Time-integrated One-pot Synthesis, X-ray Structure, and Redox Properties of Electrochromic 1,3-diarylisobenzofurans. Hamura, T.; Nakayama, R.; Hanada, K.; Sakano, Y.; Katoono, R.; Fujiwara, K.; Suzuk, T. Chem. Lett. 2013, 42, 1244–1246.
(17)A One-pot Preparation of 1,3-diarylisobenzofuran. Hamura, T.; Nakayama, R. Chem. Lett. 2013, 42, 1013–1015.

畠山琢次
(18)Triplet-Energy Control of Polycyclic Aromatic Hydrocarbons by BN Replacement: Development of Ambipolar Host Materials for Organic Light-Emitting Diodes. Hashimoto, S.; Ikuta, T.; Shiren, K.; Nakatsuka, S.; Ni, J.; Nakamura, M.; Hatakeyama, T. Chem. Mater. 2014, 26, 6265–6271.
(19)Construction of a Highly Distorted Benzene Ring in a Double Helicene.
Hashimoto, S.; Nakatsuka, S.; Nakamura, M.; Hatakeyama, T. Angew. Chem. Int. Ed. 2014, 53, 14074–14076. Highlighted in SYNFACTS, 2015, 11, 0031.
(20)One-Step Borylation of 1,3-Diaryloxybenzenes Towards Efficient Materials for Organic Light-Emitting Diodes. Hirai, H.; Nakajima, K.; Nakatsuka, S.; Shiren, K.; Ni, J.; Nomura, S.; Ikuta, T.; Hatakeyama, T. Angew. Chem. Int. Ed. 2015, 54, 13581–13585.
Highlighted in SYNFACTS, 2015, 11, 1272.
(21)Synthesis of Boron-Doped Polycyclic Aromatic Hydrocarbons by Tandem Intramolecular Electrophilic Arene Borylation. Miyamoto, F.; Nakatsuka, S.; Yamada, K.; Nakayama, K.; Hatakeyama, T. Org. Lett. 2015, 17, 6158–6161.
(22)Ultrapure Blue Thermally Activated Delayed Fluorescence Molecules: Efficient HOMO–LUMO Separation by Multiple Resonance Effect. Hatakeyama, T.; Shiren. K.; Nakajima, K.; Nomura, S.; Nakatsuka, S.; Ni, J.; Ono, Y.; Ikuta, T. Adv. Mater. 2016, in press. DOI: 10.1002/adma.201505491

山口宏
(23)Probing the Catalytic Mechanism of Copper Amine Oxidase from Arthrobacter globiformis with Halide Ions. Murakawa, T.; Hamaguchi, A.; Nakanishi, S.; Kataoka, M.; Nakai, T.; Kawano, Y.; Yamaguchi, H.; Hayashi, H.; Tanizawa, K.; Okajima, T. J. Biol. Chem. 2015, 290, 23094–23109.
(24)Trapping Mechanism of Bioactive Conformation by Intra-molecular Chaperone. Yokyama, Y.; Okumura, M.; Shimamoto, S.; Yamaguchi, H.; Hidaka, Y. Peptide Science. 2014, 51, 95–96.
(25)Inhibition of the Functional Interplay between ER Oxidoreduclin-1a (Ero1a) and Protein Disulfide Isomerase (PDI) by the Endocrine Disruptor Bisphenol A. Okumura, M.; Hashimoto, S.; Yutani, K.; Kanemura, S.; Hikima, T.; Hidaka, Y.; Ito, L.; Shiba, K.; Masui, S.; Imai, D.; Kadokura, H.; Imaoka, S.; Yamaguchi, H.; Inaba. K. J. Biol. Chem. 2014, 289, 27004–27018.
(26)Radically Different Thioredoxin Domain Arrangement of ERp46, an Efficient Disulfide Bond Introducer of the Mammalian PDI Family. Kojima, R.; Okumura, M.; Masui, S.; Kanemura, S.; Inoue, M.; Saiki, M.; Yamaguchi, H.; Hikima, T.; Suzuki, M.; Akiyama, S.; Inaba, K. Structure 2014, 22, 431–443.
(27)小分子添加剤としてアミノ酸類を用いたタンパク質の結晶化, 山口宏, 杉山成編, タンパク質結晶の最前線, pp50–57, CMC出版, (2014).
(28) Weak Interaction of an Inhibitor in the 20S Proteasome. Murakami, T.; Yamaguchi, H. Bahrudin, U.; Kita, A.; Hisatome, I.; Saeki, Y.; Tanaka, K.; Unno, M.; Morimoto, Y. Acta Crystallogr. 2014, A70, C487.
(29)Regulation of Disulfide-coupled Folding of De Novo Designed Precursor Protein. Fukumoto, S.; Yoshida, Y.; Maekawa, T.; Okumura, M.; Yamaguchi, H.; Hidaka, Y. Peptide Science 2013, 50, 265–266.
(30)Folding of De Novo Peptide Regulated by Intra-molecular Chaperones. Maekawa, T.; Fukumoto, S.; Yoshida, Y.; Okumura, M.; Yamaguchi, H.; Shimamoto, S.; Hidaka, Y. Peptide Science 2013, 49, 219–220.
(31)Bisphenol A Induces a Conformational Change in Protein Disulfide Isomerase. Okumura, M.; Hashimoto, S.; Nawata, M.; Yutani, K.; Hikima, T.; Hamada, D.; Hidaka, Y.; Ito, L.; Shiba, K.; Hosokawa, K.; Inoue, G.; Maekawa, T.; Imaoka, S.; Inaba, K.; Yamaguchi, H. Peptide Science 2013, 49, 331–332.
(32)A pH-dependent Conformational Change in a Soluble Extracellular Domain of Amyloid Precursor Protein. Kanemura, S.; Okumura. M.; Yutani, K.; Hikima, T.; Niinobe, M.; Yamaguchi, H.; Hidaka, Y. Peptide Science 2013, 49, 337–338.

金子忠昭
(33)Energy Transfer Dynamics of CdTe Quantum Dots on Epitaxial Graphene Prepared by Si Sublimation of 4H-SiC(0001). Hirose, T.; Shigemasa, H.; Kutsuma, Y.; Kaneko, T.; Tamai, N. Chemistry Letters 2014, 43, 125–127.
(34)Blinking Suppression of CdTe Quantum Dots on Epitaxial Graphene and the Analysis with Marcus Electron Transfer. Hirose, T.; Kutsuma, Y.; Kurita, A.; Kaneko, T.; Tamai, M. Applied Physics Letters 2014, 105, 083102.
(35)Crystallographic Orientation Dependence of SEM Contrast Revealed by SiC Polytypes. Ashida, K.; Kajino, T.; Kutsuma, Y.; Ohtani, N.; Kaneko, T. Journal of Vacuum Science & Technology B 2015, 33, 04E104
(36)Blinking Suppression of CdTe Quantum Dots on Epitaxial Graphene and the Analysis with Marcus Electron Transfer. Hirose, T.; Kutsuma, Y.; Kurita, A.; Kaneko, T.; Tamai, N. Appl. Phys. Lett. 2014, 105 083102

大谷清
(37)Noninvasive and Label-free Determination of Virus Infected Cells by Raman Spectroscopy. Moor, K.; Ohtani, K.; Myrzakozha, D.; Zhanserkenova, O.; Andriana, B.B.; Sato, H. J Biomed Opt 2014, 19, 67003.
(38)Cancer Cell Specific Cytotoxic Gene Expression Mediated by ARF Tumor Suppressor Promoter Constructs. Kurayoshi, K.; Ozono, E.; Iwanaga, R.; Bradford, A.P.; Komori, H.; Ohtani, K. Biochem Biophys Res Commun. 2014, 450, 240–246.
(39)Identification of Novel Target Genes Specifically Activated by Deregulated E2F in Human Normal Fibroblasts. Kitamura, H.; Ozono, E.; Iwanaga, R.; Bradford, A.P.; Okuno, J.; Shimizu, E.; Kurayoshi, K.; Kugawa, K.; Toh, H.; Ohtani, K. Genes Cells. 2015, 20, 739–757.
(40)Deregulated E2F Activity: Novel Targets and Therapeutic Potential in Cancer Treatment. Ozono, E.; Bradford, A.P.; Iwanaga, R.; Kurayoshi, K.; Araki, K.; Ohtani, K. International Biology Review 2016 in press (KEI Journals)

中山健一
(41)Hetero-Layered Organic Photovoltaic Devices Fabricated Using Soluble Pentacene Photoprecursors. Motoyama, T.; Kiyota, T.; Yamada, H.; Nakayama, K. Sol. Energ. Mater. Sol. Cell. 2013, 114, 156–160.
(42)Characterization and Field-Effect Transistor Performance of Printed Pentacene Films Prepared by Photoconversion of the Soluble Precursor. Nakayama, K.; Ohashi, C.; Oikawa, Y.; Motoyama, T.; Yamada, H. J. Mater. Chem. A 2013, 1, 6244–6251.
(43)Photo-conversion and Structural Properties of the Drop-casted Films of 6,13-Pentacene Diketone. Ohashi, C.; Yamada, H.; Nakayama, K. Mol. Cryst. Liq. Cryst. 2013, 580, 103–109.
(44)Doping Effect of CBP in Bulk-heterojunction Photovoltaic Devices Composed of P3HT and Soluble Perylene Bisimide. Tani, Y. Seki, T.; Lin, X.; Kurata, H.; Yagai, S.; Nakayama, K. Mol. Cryst. Liq. Cryst. 2013, 578, 88–94.
(45)Polymer Material Dependence in the Polymer/small Molecule Metal-base Organic Transistors. Umetsu, K.; Akiba, R.; Nakayama, K.; Kido, J. Mol. Cryst. Liq. Cryst. 2013, 580, 117–124.
(46)Indolocarbazoles End-capped with Diketopyrrolopyrrole Dyes for Solution-processed Organic Solar Cells. Lin, X.; Tani, Y.; Nakayama, K.; Yagai, S. J. Mater. Chem. A 2013, 1, 14686–14691.
(47)Synthesis and Photoreactivity of α-diketone-type Precursors of Acenes and Their Use in Organic-device Fabrication, Suzuki, M.; Aotake, T.; Yamaguchi, Y.; Noguchi, N.; Nakano, H.; Nakayama, K.; Yamada, H. J. Photochem. Photobiol. 2014, 18, 50−70.
(48)Solution-processed Anthradithiophene-PCBM p-n Junction Photovoltaic Cells Fabricated by Using the Photoprecursor Method, Yamada, H.; Yamaguchi, Y.; Katoh, R.; Motoyama, T.; Aotake, T.; Kuzuhara, D.; Suzuki, M.; Okujima, T.; Uno, H.; Aratani, N.; Nakayama, K. Chem. Commun. 2014, 49, 11638−11640.
(49)N-type Metal-Base Organic Transistors Having Thin Collector Layers, Ueno, Y.; Yashima, T.; Kido, J.; Nakayama, K. Jpn. J. Appl. Phys. 2014, 53, 01AC03−1−4.
(50)Bulk-Heterojunction Organic Photovoltaic Devices Fabricated Using Asymmetric Soluble Anthracene Core Photoprecursors, Motoyama, T.; Sugii, S.; Ikeda, S.; Yamaguchi, Y.; Yamada, H.; Nakayama, K. Jpn. J. Appl. Phys. 2014, 53, 01AB02−1−4.
(51)A Morphology Control Layer of a Pyrene Dimer Enhancing Efficiency in Small Molecule Organic Photovoltaic Cells, Kawata, S.; Pu, Y. -J.; Ohashi, C.; Nakayama, K.; Ziruo, H.; Kido, J. J. Mater. Chem. 2014, 2, 501−509.
(52)Terazulene: A High-Performance n-Type Organic Field-Effect Transistor Based on Molecular Orbital Distribution Control, Yamaguchi, Y.; Ogawa, K.; Nakayama, K.; Ohba, Y.; Katagiri, H. J. Am. Chem. Soc. 2013, 135, 19095−19098.
(53)A Perylene Bisimide Organogelator for Chlorinated Solvents, Lin, X.; Hirono, M.; Kurata, H.; Seki, T.; Maruya, Y.; Nakayama, K.; Yagai, S. Asian. J. Org. Chem. 2014, 3, 128−132.
(54)Self-organized One-dimensional Columns of Benzo[b]thiophene-fused Tetraazaporphyrins, Suzuki, H.; Yamada, N.; Nakayama, K.; Kimura, M. J. Porphy. Phthal. 2014, 18, 259−266.
(55)Supramolecular Engineering of Oligothiophene Nanorods without Insulators: Hierarchical Association of Rosettes and Photovoltaic Properties, Yagai, S.; Suzuki, M.; Lin, X.; Gushiken, M.; Noguchi, T.; Karatsu, T.; Kitamura, A.; Saeki, A.; Seki, S.; Kikkawa, Y.; Tani, Y.; Nakayama, K. Chem. Eur. J. 2014, 20, 16128−16137.
(56)Photoprecursor Approach as an Effective Means for Preparing Multilayer Organic Semiconducting Thin Films by Solution Processes, Yamaguchi, Y.; Suzuki, M.; Motoyama, T.; Sugii, S.; Katagiri, C.; Katsuya, T.; Ikeda, S.; Yamada, H.; Nakayama, K. Sci. Rep. 2014, 4v, 7151.
(57)Carrier Dynamics in Pentacene |C60 Bilayer Solar Cell Investigated through the Magnetoconductance, Omori, T.; Wakikawa, Y.; Miura, T.; Yamaguchi, Y.; Nakayama, K.; Ikoma, T. J. Phys. Chemv. C, 2014, 118, 28418−28424.
(58)Effect of Alkyl Substituents: 5,15-bis(trimethylsilylethynyl)- vs. 5,15-bis(triisopropylsilylethynyl)-tetrabenzoporphyrins and Their Metal Complexes, Takahashi, K.; Yamada, N.; Kumagai, D.; Kuzuhara, D.; Suzuki, M.; Yamaguchi, Y.; Aratani, N.; Nakayama, K.; Yamada, H. J. Porphy. Phthal. 2015, 19, 465−478.
(59)Evaluation of the Charge Transfer Efficiency of Organic Thin-film Photovoltaic Devices Fabricated Using a Photoprecursor Approach, Masuo, S.; Sato, W.; Yamaguchi, Y.; Suzuki, M.; Nakayama, K.; Yamada, H. Photochem. Photobiol. Sci. 2015, 14, 883−890.
(60)Evaluation of Semiconducting Molecular Thin Films Solution-processed via the Photoprecursor Approach: the Case of Hexyl-substituted Thienoanthracenes, Quinton, C.; Suzuki, M.; Kaneshige, Y.; Tatenaka, Y.; Katagiri, C.; Yamaguchi, Y.; Kuzuhara, D.; Aratani, N.; Nakayama, K.; Yamada, H. J. Mater. Chem. 2015, 3, 5995−6005.
(61)Novel Design of Carbazole-Based Donor_Acceptor Molecules for Fullerene-Free Organic Photovoltaic Devices, Michinobu, T.; Yamada, N.; Washino, Y.; Nakayama, K. J. Nanosci. Nanotechnol. 2015, 15, accepted.

Dulce PAPY-Garcia
(62)HS3ST2 Expression is Critical for the Abnormal Phosphorylation of Tau in Alzheimer's Disease-related Tau Pathology, Sepulveda-Diaz, J. E.; Alavi Naini, S. M.; Huynh, M. B.; Ouidja, M. O.; Yanicostas, C.; Chantepie, S.; Villares, J.; Lamari, F.; Jospin, E.; van Kuppevelt, T. H.; Mensah-Nyagan, A. G.; Raisman-Vozari, R.; Soussi-Yanicostas, N.; Papy-Garcia, D. Brain. 2015, 138, 1339−1354.
(63)A Fine Structural Modification of Glycosaminoglycans is Correlated with the Progression of Muscle Regeneration after Ischaemia: towards a Matrix-based therapy?, Chevalier, F.; Arnaud, D.; Henault, E.; Guillevic, O.; Siñeriz, F.; Ponsen, A. C.; Papy-Garcia, D.; Barritault, D.; Letourneur, D.; Uzan G.; Meddahi-Pellé, A.; Hlawaty, H.; Albanese, P. Eur. Cell Mater. 2015, 30, 51−68.
(64)Modulation of Inflammation and Angiogenesis and Changes in ECM GAG-activity via Dual Delivery of Nucleic Acids, Browne, S.; Monaghan, M. G.; Brauchle, E.; Berrio, D. C.; Chantepie, S.; Papy-Garcia, D.; Schenke-Layland, K.; Pandit A. Biomaterials. 2015, 69, 133−147.
(65)New Methods Based on Capillary Electrophoresis for in vitro Evaluation of Protein Tau Phosphorylation by Glycogen Synthase Kinase 3-β, Nehmé, H.; Chantepie, S.; Defert, J.; Morin, P.; Papy-Garcia D.; Nehmé, R. Anal. Bioanal. Chem. 2015, 407, 2821−2828.
(66)New Roles of Glycosaminoglycans in α-synuclein Aggregation in a Cellular Model of Parkinson Disease, Lehri-Boufala, S.; Ouidja, M. O.; Barbier-Chassefière, V.; Hénault, E.; Raisman-Vozari, R.; Garrigue-Antar, L.; Papy-Garcia, D.; Morin, C. PLoS One. 2015, 24, e0116641.
(67)Glycosaminoglycan Modifications in Duchenne Muscular Dystrophy: Specific Remodeling of Chondroitin Sulfate/dermatan Sulfate, Negroni, E.; Henault, E.; Chevalier, F.; Gilbert-Sirieix, M.; Van Kuppevelt, T. H.; Papy-Garcia, D.; Uzan G.; Albanese, P. J. Neuropathol. Exp. Neurol. 2014, 73, 789−797.
(68)Structural Characterization of Heparin-induced GAPDH Protofibrils Preventing α-synuclein Oligomeric Species Toxicity, Avila, C. L.; Torres-Bugeau, C. M.; Barbosa, L. R.; Morandé Sales, E.; Ouidja, M. O.; Socías, S. B.; Celej, M. S.; Raisman-Vozari, R.; Papy-Garcia, D.; Itri, R.; Chehin, R. N. J. Biol. Chem. 2014, 289, 13838−13850.
(69)Live Imaging of Prions Reveals Nascent PrPSc in Cell-surface, Raft-associated Amyloid Strings and Webs. Rouvinski, A.; Karniely, S.; Kounin, M.; Moussa, S.; Goldberg, MD.; Warburg, G.; Lyakhovetsky, R.; Papy-Garcia, D.; Kutzsche, J.; Korth, C.; Carlson, GA.; Godsave, SF.; Peters, PJ.; Luhr, K.; Kristensson, K.; Taraboulos, A. J. Cell. Biol. 2014, 204, 423–441.
(70)Greater Glycosaminoglycan Content in Human Patellar Tendon Biopsies is Associated with More Pain and a Lower VISA Score. Attia M, Scott A, Carpentier G, Lian, O.; Van Kuppevelt, T.; Gossard, C.; Papy-Garcia, D.; Tassoni, MC.; Martelly, I. Br J. Sports Med. 2014, 48, 469–475.
(71)Heparan Sulfate Proteoglycans Mediate Internalization and Propagation of Specific Proteopathic Seeds. Holmes, BB.; Devos, SL.; Kfoury, N.; Li, M.; Jacks, R.; Yanamandra, K.; Ouidja, MO.; Brodsky, FM.; Marasa, J.; Bagchi, DP.; Kotzbauer, PT.; Miller, TM.; Papy-Garcia, D.; Diamond, MI. Proc Natl Acad Sci U S A. 2013, 110, 3138–3147.
(72)Glycosaminoglycan Mimetic Associated to Human Mesenchymal Stem Cell-based Scaffolds Inhibit Ectopic Bone Formation, but Induce Angiogenesis in Vivo. Frescaline, G.; Bouderlique, T.; Mansoor, L.; Carpentier, G.; Baroukh, B.; Sineriz, F.; Trouillas, M.; Saffar, JL.; Courty, J.; Lataillade, JJ.; Papy-Garcia, D.; Albanese, P. Tissue Eng. Part A. 2013, 19, 1641–1653.
(73)Self-evolving Oxidative Stress with Identifiable Pre- and Postmitochondrial Phases in PC12 Cells. Zhang, G.; Morin, C.; Zhu, X.; Bao Huynh, M.; Ouidir Ouidja, M.; Sepulveda-Diaz, JE.; Raisman-Vozari, R.; Li, P.; Papy-Garcia, D. J. Neurosci Res. 2013, 91, 273–284.
(74)Molecular Imprinting Technology for Specific Recognition of Heparan Sulfate Like Disaccharides.Singabraya D. Bultel, L.; Siñeriz, F.; Mothère, M.; Lesur, D.; Kovensky, J.; Papy-Garcia, D. Talanta. 2012, 15, 833–839.
(75)Heparin Affin Regulatory Peptide (HARP) Modulates the Endogenous Anticoagulant Activity of Heparin and Heparan Sulfate Mimetics. Mejdoubi-Charef, N.; Courty, J.; Sineriz, F.; Papy-Garcia, D.; Charef, S. Basic Clin Pharmacol Toxicol. 2012, 111, 296–302.
(76)Age-related Changes in Glycosaminoglycans from Rat Myocardium Involve Altered Capacities to Potentiate Growth Factors Functions and Heparan Sulfate Altered Sulfation. Huynh, MB.; Morin, C.; Carpentier, G.; Garcia-Filipe, S.; Talhas-Perret, S.; Barbier-Chassefière, V.; van Kuppevelt, TH.; Martelly, I.; Albanese, P.; Papy-Garcia, D. J. Biol Chem. 2012, 287, 11363–11373.
(77)Glycosaminoglycans Mimetics Potentiate the Clonogenicity, Proliferation, Migration and Differentiation Properties of Rat Mesenchymal Stem Cells. Frescaline, G.; Bouderlique, T.; Huynh, MB.; Papy-Garcia, D.; Courty, J.; Albanese, P. Stem. Cell. Res. 2012, 8, 180–192.
(78)Characterization of Heparin-induced Glyceraldehyde-3-phosphate Dehydrogenase Early Amyloid-like Oligomers and their Implication on α-Synuclein Aggregation. Torres-Bugeau, CM.; Avila, CL.; Raisman-Vozari, R.; Papy-Garcia, D.; Itri, R.; Barbosa, LR.; Cortez, LM.; Sim, VL.; Chehin, RN. J. Biol Chem. 2012, 287, 2398–2409.
(79)Glycosaminoglycans from Aged Human Hippocampus Have Altered Capacities to Regulate Trophic Factors Activities but not Aβ42 Peptide Toxicity. Huynh, MB.; Villares, J.; Sepúlveda Díaz, JE.; Christiaans, S.; Carpentier, G.; Ouidja, MO.; Sissoeff, L.; Raisman-Vozari, R.; Papy-Garcia, D. Neurobiol Aging. 2012, 33(5) :1005.e11–22. (Article selected by 'Global Medical Discovery' as a breaking article considered to be of importance to the drug discovery process).

島本啓子
(80)Elucidation of Excitatory Neurotransmission and Membrane Protein Integration Mechanisms. Shimamoto, K. (in press) Bull. Chem. Soc. Jpn.
(81)A Fluorescent Ligand with High Affinity towards G-Quadruplexes. Tera, M.; Hirokawa, T.; Okabe, S.; Sugahara, K.; Seimiya, H.; Shimamoto, K.; Chem. Eur. J. 2015, 21, 14519–14528.
(82)Solid-state NMR Spectra of Lipid-anchored Proteins Under Magic Angle Spinning. Nomura, K.; Harada, E.; Sugase, K.; Shimamoto, K. J. Phys.Chem. B. 2014, 118, 2405–2413.
(83)Glycolipozyme Membrane Protein Integrase (MPIase): Recent data. Nishiyama, K.; Shimamoto, K. BioMolecular Concepts, 2014, 5, 429–438.
(84)A Novel Glutamate Transporter Blocker, LL-TBOA, Attenuates Ischemic Injuri in the Isolated, Perfused Rat Heart Despite Low Transporter Levels. Martinov, V.; Dehnes, Y.; Holmseth, S.; Shimamoto, K.; Danbolt, N.C.; Valen, G. Eur. J. Cardiothorac. Surg. 2014, 45, 710–716.
(85)Kinetic Resolution and Stereoselective Synthesis of 3-Substituted Aspartic Acids by Using Engineered Methylaspartate Ammonia Lyases. Raj, H.; Szymanski, W.; de Villiers, J.; Puthan Veetil, V.; Quax, W.J.; Shimamoto, K.; Janssen, D.B.; Feringa, B.L.; Poelarends, G. J. Chem. Eur. J., 2013, 19, 11148–11152.

伊東秀之
(86)Proanthocyanidins in an Astringent Persimmon Inhibit Salmonella Pathogenicity Island 1 (SPI1) Secretion. Morita, A.; Tai, A.; Ito, H.; Ganeko, N.; Aizawa, S.-I. J. Sci. Food Agric., 2015, Article first published online: 1 JUL 2015.
(87)Cleaving Effect of Pomegranate (Punica Granatum) Extract on Crosslink Derived from Advanced Glycation Endproducts. Yagi, M.; Mitsuhashi, R.; Watanabe, A.; Moritani, Y.; Naito, J.; Lanny, P.; Ito, H.; Nagatomo, A.; Nishida, N.; Yonei, Y. Glycative Stress Res., 2015 2, 58–66.
(88)Inhibition of Leukocyte-type 12-Lipoxygenase by Guava Tea Leaves Prevents Development of Atherosclerosis. Takahashi, Y.; Otsuki, A.; Mori, Y.; Kawakami, Y.; and Ito, H. Food Chem., 2015, 186, 2–5.
(89)Quinolone Analogues 16: A facile D–H Exchange for 3-H Proton of 2-Substituted 4-Quinolones in Acidic Media. Kurasawa, Y.; Yoshida, K.; Yamazaki, N.; Sasaki, K.; Zamami, Y.; Min, Z.; Togi, A.; Ito, H.; Kaji, K.; Fukuya, H. J. Heterocyclic Chem., 2014, 51, 1821–1829.
(90)Synthesis and Antimalarial Activity of 4-phenyl-1-(1-triazolylmethyl-4-quinolon-3-ylcarbonyl)semicarbazide and Related Compounds. Kurasawa, Y.; Yoshida, K.; Yamazaki, N.; Sasaki, K.; Zamami, Y.; Min, Z.; Togi, A.; Ito, H.; Kaji, K.; Fukuya, H. J. Heterocyclic Chem., 2014, 51, 249–254.
(91)Quinolone Analogues 14: Synthesis of Antimalarial 1-aryl-3-(4-quinolon-2-yl)ureas and Related Compounds. Kurasawa, Y.; Yoshida, K.; Yamazaki, N.; Sasaki, K.; Zamami, Y.; Min, Z.; Togi, A.; Ito, H.; Kaji, K.; Fukuya, H. J. Heterocyclic Chem. 2014, 51, E241–E248.
(92)Quinolone Analogues 13: Synthesis of Novel 1,1’-(2-methylenepropane-1,3-diyl)di(4-quinolone-3-carboxylate) and Related Compounds. Kurasawa, Y.; Yoshida, K.; Yamazaki, N.; Sasaki, K.; Zamami, Y.; Min, Z.; Togi, A.; Ito, H.; Kaji, K.; Fukuya, H. J. Heterocyclic Chem. 2014, 51, 1720–1726.
(93)A Simple Efficient Synthesis and Biological Evaluation of 3-O-ethylascorbic acid. Tai, A.; Aburada, M.; Ito, H. Biosci. Biotech. Biochem. 2014, 78, 1984–1987.
(94)Antioxidative Properties of Ascorbigen in Using Multiple Antioxidant Assays. Tai, A.; Fukunaga, K.; Ohno, A.; Ito, H. Biosci. Biotech. Biochem. 2014, 78, 1723–1730.
(95)Inhibitory Effects of Pomegranate Extracts on Recombinant Human Maltase-glucoamylase. Kawakami, K.; Li, P.; Uraji, M.; Hatanaka, T.; Ito, H. J. Food Sci. 2014, 79, 1848–1852.
(96)Synthesis and Biological Evaluation of New BSH-conjugated Chlorin Derivatives as Agents for Both Photodynamic Therapy and Boron Neutron Capture Therapy of Cancer. Asano, R.; Nagami, A.; Fukumoto, Y.; Miura, K.; Yazama, F.; Ito, H.; Sakata, I.; Tai, A. J. Photochem. Photobiol B. 2014, 140, 140–149.
(97)Effects of Young Barley Leaf Powder on Gastrointestinal Functions in Rats and its Efficacy-related Physicochemical Properties. Ikeguchi, M.; Tsubata, M.; Takano, A.; Kamiya, T.; Takagaki, K.; Ito, H.; Sugawa-Katayama Y.; Tsuji, H. Evid. Based Complement. Alternat. Med. 2014, Article ID 974840, 7 pages.
(98)Biotransformation of α-mangostin by Colletotrichum sp. MT02 and Phomopsis euphorbiae K12. Arunrattiyakorn, P.; Suwannasai, N.; Aree, T.; Kanokmedhakul, S.; Ito, H.; Kanzaki, H. J. Mol. Catal. B: Enzym. 2014, 102, 174–179.
(99)Synthesis and Biological Evaluation of New Boron-containing Chlorin Derivatives as Agents for Both Photodynamic Therapy and Boron Neutron Capture Therapy of Cancer. Asano, R.; Nagami, A.; Fukumoto, Y.; Miura, K.; Yazama, F.; Ito, H.; Sakata, I.; Tai, A. Bioorg. Med. Chem. Lett. 2014, 24, 1339–1343.
(100)Ellagitannin Oligomers and a Neolignan from Pomegranate Arils and Their Inhibitory Effects on the Formation of Advanced Glycation End Products. Ito, H.; Li, P.; Koreishi, M.; Nagatomo, A.; Nishida, N.; Yoshida, T. Food Chem. 2014, 152, 323–330.
(101)Components of Foods Inhibit a Drug Exporter, Human Multidrug and Toxin Extrusion Transporter 1. Kawasaki, T.; Ito, H.; Omote, H. Biol. Pharm. Bull. 2014 37 (2) , 292–297.
(102)加水分解性ポリフェノール,エラジタンニンの生体内代謝産物とその機能 伊東秀之 バイオサイエンスとインダストリー 2014, 72, 123–124.
(103)Molecular Probes in Tandem Electrospray Ionization Mass Spectrometry: Application to Tracing Chemical Changes of Specific Phospholipid Molecular Species. Tominaga, H.; Ishihara, T.; Shah, A.K.M.A.; Shimizu, R.; Onyango, A.N.; Ito, H.; Suzuki, T.; Kondo, Y.; Koaze, H.; Takahashi, K.; Baba, N. Am. J. Anal. Chem. 2013, 4 (10B), 16–26.
(104)Pancreatic Lipase Inhibitory Gallotannins fromGalla rhois with Inhibitory Effects on Adipocyte Differentiation in 3T3-L1 Cells. Kwon, O. J.; Bae, J.-S.; Lee, H. Y.; Hwang, J.-Y.; Lee, E.-W.; Ito, H.; Kim, T. H. Molecules 2013, 18, 10629–10638.
(105)Roxbin B is Cuspinin: Structural Revision and Total Synthesis. Yamaguchi, S.; Hirokane, T.; Yoshida, T.; Tanaka, T.; Hatano, T.; Ito, H.; Nonaka, G.; and Yamada, H. J. Org. Chem. 2013, 78, 5410–5418.
(106)Two New Monoterpene Glycosides from Qing Shan Lu Shui Tea with Inhibitory Effects on Leukocyte-type 12-lipoxygenase Activity. Ito, H.; Otsuki, A.; Mori, H.; Li, P.; Kinoshita, M.; Kawakami, Y.; Tsuji, H.; Fang, D.Z.; Takahashi, Y. Molecules 2013, 18, 4257–4266.
(107)Highly Efficient and Regioselective Production of an Erythorbic acid glucoside using cyclodextrin glucanotransferase from Thermoanaerobacter sp. and Amyloglucosidase. Tai, A.; Iwaoka, Y.; Ito, H. J. Mol. Catal. B Enzym. 2013, 92, 19–23.
(108)Synthesis and Biological Evaluation of New Chlorin Derivatives as Potential Photosensitizers for Photodynamic Therapy. Asano, R.; Nagami, A.; Fukumoto, Y.; Yazama, F.; Ito, H.; Sakata, I.; Tai, A. Bioorg. Med. Chem. 2013, 21, 2298–2304.
(109)Steroids from Dysoxylum grande (Meliaceae) Leaves. Waha, L.K.; Abasb, F.; Cordelld G.A.; Ito, H.; Ismail I.S. Steroids 2013, 78, 210–219.


Patents ––––––––––
知的財産権

Books ––––––––––
著書

(1)島本啓子, 西山賢一 タンパク質ではない酵素? -タンパク質膜挿入の鍵を握るグライコリポザイム (2014)「実験医学増刊 驚愕の代謝システム」  実験医学, 32(15), 115-122.
(2)西山賢一, 島本啓子 膜タンパク質の鍵は糖脂質にあり -すべての生体膜挿入に必要な因子を求めて- (2013) 化学 68, 30-34